We have a lot of pine trees in our neighborhood that block afternoon light, and the part of the roof directly over the tank slants southward to block even more light out. This wasn't an option for us. You get best light output when the sun is directly overhead and when your solatube is placed in a straight, vertical line. The longer the tube you use and the more bends you have in it, the less efficient output you'll have.
I've read that the light needs to be supplemented to get better SPS colors, but most seem to be pleased with the $$$ they save on the e-bill.